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  • Hematopoietic Stem Cell Transplantation Associated Thrombotic Microangiopathy TTP(TMA): Report of Two Cases and Review of the Literature
  • 廖艳华.造血干细胞移植相关血栓性微血管病TTP(TMA)2例报道并文献复习[J].内科急危重症杂志,2016,22(1):
    DOI：
    CN KeyWords:  移植相关血栓性微血管病  纤维素–血小板微血栓  血浆置换
    EN KeyWords:
    Fund Project:
    Author:廖艳华
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          目的：探讨移植相关血栓性微血管病(TA-TMA)的病因、发病机理、临床表现及早期诊断和治疗。方法：用血浆置换治疗2例TMA同时辅以皮质激素和长春新碱等治疗。结果：一例因血小板未植活并输注无效致颅内出血而死亡；一例获得缓解。结论：TA-TMA的发生与性别、年龄,HLA配型,预处理方案,感染,aGVHD,植入不良,及某些药物等因素有关 。发病机制是毛细血管内纤维素-血小板血栓形成。减停CSA,早期血浆置换辅以长春新碱是目前治疗本病的最佳方法。
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