| 刘家琦.抗凝治疗在老年重症社区获得性肺炎治疗中的研究进展[J].内科急危重症杂志,2026,32(5):495-500 |
| 抗凝治疗在老年重症社区获得性肺炎治疗中的研究进展 |
| Advances in anticoagulant therapy for severe community-acquired pneumonia in older adults |
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| DOI：10.11768/nkjwzzzz.202504100488 |
| 中文关键词: 抗凝治疗 重症社区获得性肺炎 老年人 |
| 英文关键词: Anticoagulant therapy Severe community -acquired pneumonia Elderly |
| 基金项目:成都市科技局技术创新研发项目（2024 -YF05 -01301 -SN） |
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| 中文摘要: |
| 摘要 老年重症社区获得性肺炎（sCAP）是一种具有高发病率、死亡率和经济负担的疾病，随着抗生素的耐药率增加，以及老年sCAP患者的多系统受累特点，需进一步研究综合治疗方法。老年sCAP患者常伴有全身凝血及纤维溶解系统的异常。近年来，抗凝治疗在老年sCAP患者中的应用逐渐受到关注，不仅用于预防和治疗静脉血栓栓塞，还可能提高患者总体预后。本文探讨老年sCAP抗凝治疗的现状、研究进展以及未来研究方向。 |
| 英文摘要: |
| Abstract Severe community-acquired pneumonia (sCAP) in older adults is characterized by high incidence and mortality rates and a substantial economic burden. Increasing rates of antibiotic resistance and multisystem involvement in older patients with sCAP highlight the need for further research into comprehensive treatment strategies. Older patients with sCAP often exhibit abnormalities in systemic coagulation and fibrinolysis. In recent years, anticoagulant therapy has attracted increasing attention in older patients with sCAP, not only for the prevention and treatment of venous thromboembolism but also for its potential to improve overall prognosis. This review discusses the current status, research advances, and future research directions of anticoagulant therapy in older patients with sCAP. |
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