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邹兴怡.病毒相关免疫性血小板减少症的研究进展[J].内科急危重症杂志,2026,32(3):290-295
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| DOI：10.11768/nkjwzzzz20260317 |
| 中文关键词: 免疫性血小板减少症 病毒感染 发病机制 治疗 |
| 英文关键词:Immune thrombocytopenia Viral infection Pathogenesis Therapy |
| 基金项目:湖北省自然科学基金（2023AFB606） |
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| 摘要点击次数: 117 |
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| 中文摘要: |
| 摘要 免疫性血小板减少症(ITP)是一种由免疫介导的血小板破坏增加和/或生成减少导致的出血性疾病。近年来，病毒感染与ITP发病的关联日益受到关注。本文阐述病毒相关ITP的流行病学特征、发病机制、临床表现、诊断和治疗策略的最新研究进展，重点探讨Epstein-Barr病毒、巨细胞病毒、肝炎病毒、人类免疫缺陷病毒等常见病毒在ITP发病中的作用，并对其未来研究方向进行展望。 |
| 英文摘要: |
| Abstract Immune thrombocytopenia (ITP) is a bleeding disorder caused by immune-mediated increase in platelet destruction and/or decrease in platelet production. In recent years, the association between viral infections and the pathogenesis of ITP has attracted increasing attention. This article describes the latest research progress on the epidemiological characteristics, pathogenesis, clinical manifestations, diagnosis, and treatment strategies of virus-related ITP, with a focus on the roles of common viruses such as Epstein-Barr virus（EBV）, cytomegalovirus（CMV）, hepatitis viruses, and human immunodeficiency virus（HIV） in the pathogenesis of ITP, and provides perspectives on future research directions in this field. |
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